Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15.

doi:10.1002/humu.21145

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Article

Allelic imbalance (AI) identifies novel tissue-specific cis-regulatory variation for human UGT2B15.

Human mutation - 1 Jan 2010

Sun Chang, Southard Catherine, Witonsky David B, Olopade Olufunmilayo I, Di Rienzo Anna

Abstract excerpt

Allelic imbalance (AI) is a powerful tool to identify cis-regulatory variation for gene expression. UGT2B15 is an important enzyme involved in the metabolism of multiple endobiotics and xenobiotics. In this study, we measured the relative expression of two alleles at this gene by using SNP rs1902023:G>T. An excess of the G over the T allele was consistently observed in liver (P<0.001), but not in breast (P=0.06)...

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PMID: 19847790
DOI: 10.1002/humu.21145
PMCID: PMC2922057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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