Differential allelic expression of c.1568C > A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3'UTR.

doi:10.1016/j.gene.2011.04.001

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Article

Differential allelic expression of c.1568C > A at UGT2B15 is due to variation in a novel cis-regulatory element in the 3'UTR.

Gene - 15 Jul 2011

Sun Chang, Southard Catherine, Olopade Olufunmilayo I, Di Rienzo Anna

Abstract excerpt

Differential allelic expression (DAE) is a powerful tool to identify cis-regulatory elements for gene expression. The UDP-glucuronosyltransferase 2 family, polypeptide B15 (UGT2B15), is an important enzyme involved in the metabolism of multiple endobiotics and xenobiotics. In the present study, we measured the relative expression of two alleles at SNP c.1568C>A (rs4148269) in this gene, which causes an amino acid...

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PMID: 21513781
DOI: 10.1016/j.gene.2011.04.001
PMCID: PMC3105206

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