Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population.

Metabolism: clinical and experimental - 1 Apr 2010

Vimaleswaran Karani S, Radha Venkatesan, Jayapriya Munuguru Gopal, Ghosh Saurabh, Majumder Partha P, Rao M R Sathyanarayana, Mohan Viswanathan

Abstract excerpt

Peroxisome proliferator-activated receptor-gamma2 (PPARG2) is a nuclear hormone receptor of ligand-dependent transcription factor involved in adipogenesis and a molecular target of the insulin sensitizers thiazolidinediones. We addressed the question of whether the 3 variants (-1279G/A, Pro12Ala, and His478His) in the PPARG2 gene are associated with type 2 diabetes mellitus and its related traits in a South...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to PPARG gene

Share to Genotype

Share to Haplotypes

Share to PPAR gamma

Source

Identifiers

PMID: 19846173
DOI: 10.1016/j.metabol.2009.07.034

Genes

PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population.PMID 19846173Read ↗

PPARG and ADIPOQ gene polymorphisms increase type 2 diabetes mellitus risk in Asian Indian Sikhs: Pro12Ala still remains as the strongest predictor.Semantic proximity Read ↗

Association of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene polymorphisms and type 2 diabetes mellitus: a meta-analysis.Semantic proximity Read ↗

The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.Semantic proximity Read ↗

Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.Semantic proximity Read ↗

The peroxisome proliferator-activated receptor-gamma2 Pro12A1a variant: association with type 2 diabetes and trait differences.Semantic proximity Read ↗

Peroxisome proliferator activated receptor gamma gene variants influence susceptibility and insulin related traits in Indian women with polycystic ovary syndrome.Semantic proximity Read ↗

Association of the PPARGC1A gene polymorphism with diabetic nephropathy in an Asian Indian population (CURES-41).Semantic proximity Read ↗

A functional variant in the peroxisome proliferator-activated receptor gamma2 promoter is associated with predictors of obesity and type 2 diabetes in Pima Indians.Semantic proximity Read ↗

Peroxisome proliferator‐activated receptor‐γ co‐activator‐1α (PGC‐1α) gene polymorphisms and their relationship to Type 2 diabetes in Asian IndiansSemantic proximity Read ↗

Association of Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor gamma 2 (PPARγ2) Gene with Type 2 Diabetes Mellitus in Ethnic Kashmiri Population.Semantic proximity Read ↗

Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.Semantic proximity Read ↗

Associations of type 2 diabetes with common variants in PPARD and the modifying effect of vitamin D among middle-aged and elderly Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.