Article
Associations of type 2 diabetes with common variants in PPARD and the modifying effect of vitamin D among middle-aged and elderly Chinese.
PloS one - 1 Jan 2012
Lu Ling, Wu Ying, Qi Qibin, Liu Chen, Gan Wei, Zhu Jingwen, Li Huaixing, Lin Xu
Abstract excerpt
BACKGROUND: Previous studies have identified that variants in peroxisome proliferator-activated receptor PPAR-δ (PPARD), a target gene of vitamin D, were significantly associated with fasting glucose and insulin sensitivity in European populations. This current study sought to determine (1) whether the genetic associations of PPARD variants with type 2 diabetes and its related traits could be replicated in...
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