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Association of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene polymorphisms and type 2 diabetes mellitus: a meta-analysis.

Diabetes/metabolism research and reviews - 1 Feb 2011

Yang Ying, Mo Xingbo, Chen Shufeng, Lu Xiangfeng, Gu Dongfeng

Abstract excerpt

BACKGROUND: The association between peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) polymorphisms and type 2 diabetes mellitus (T2DM) has been investigated in several studies, but these studies yielded contradictory results. We conducted a meta-analysis to assess the association between three polymorphisms (Gly482Ser, Thr394Thr and Thr612Met) in PPARGC1A and T2DM. METHODS: A...

Topics

Diabetes Mellitus, Type 2
Genetic Predisposition to Disease
Heat-Shock Proteins
Humans
Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha
Polymorphism, Genetic
Risk Factors
Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21294239
DOI: 10.1002/dmrr.1158

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Association of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PPARGC1A) gene polymorphisms and type 2 diabetes mellitus: a meta-analysis.PMID 21294239Read ↗

The association between the peroxisome proliferator-activated receptor-gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis.Semantic proximity Read ↗

PPARGC1A rs3736265 G>A polymorphism is associated with decreased risk of type 2 diabetes mellitus and fasting plasma glucose level.Semantic proximity Read ↗

Meta-analysis of the Gly482Ser variant in PPARGC1A in type 2 diabetes and related phenotypes.Semantic proximity Read ↗

PPARG (Pro12Ala) genetic variant and risk of T2DM: a systematic review and meta-analysis.Semantic proximity Read ↗

Meta-analysis demonstrates Gly482Ser variant of PPARGC1A is associated with components of metabolic syndrome within Asian populations.Semantic proximity Read ↗

Evaluation of the association between the PPARGC1A genetic polymorphisms and type 2 diabetes in Han Chinese population.Semantic proximity Read ↗

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[Relationship between PPARγ2 Pro12Ala polymorphism and type 2 diabetes mellitus in Chinese Han population: a Meta-analysis].Semantic proximity Read ↗

Association of the PPARGC1A gene polymorphism with diabetic nephropathy in an Asian Indian population (CURES-41).Semantic proximity Read ↗

The Gly482Ser polymorphism of the peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is associated with type 2 diabetes in Tunisian population.Semantic proximity Read ↗

Peroxisome proliferator‐activated receptor‐γ co‐activator‐1α (PGC‐1α) gene polymorphisms and their relationship to Type 2 diabetes in Asian IndiansSemantic proximity Read ↗

[PPARGC1A gene Thr394Thr G/A polymorphism and its association with type 2 diabetes mellitus and insulin resistance in a Chinese population].Semantic proximity Read ↗

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