Article
Role of genetic polymorphism peroxisome proliferator-activated receptor-gamma2 Pro12Ala on ethnic susceptibility to diabetes in South-Asian and Caucasian subjects: Evidence for heterogeneity.
Diabetes care - 1 May 2006
Radha Venkatesan, Vimaleswaran Karani S, Babu Hunsur Narayan S, Abate Nicola, Chandalia Manisha, Satija Pankaj, Grundy Scott M, Ghosh Saurabh, Majumder Partha P, Deepa Raj, Rao Sathyanarayana M R, Mohan Viswanathan
Abstract excerpt
OBJECTIVE: To determine whether the peroxisome proliferator-activated receptor (PPAR)-gamma Pro12ala polymorphism modulates susceptibility to diabetes in South Asians. RESEARCH DESIGN AND METHODS: South Asians (n = 697) and Caucasians (n = 457) living in Dallas/Forth Worth, Texas, and South Asians living in Chennai, India (n = 1,619), were enrolled for this study. PPAR-gamma Pro12Ala was determined using...
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