Article
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk.
BMC medical genetics - 3 Jul 2008
Sanghera Dharambir K, Ortega Lyda, Han Shizhong, Singh Jairup, Ralhan Sarju K, Wander Gurpreet S, Mehra Narinder K, Mulvihill John J, Ferrell Robert E, Nath Swapan K, Kamboh Mohammed I
Abstract excerpt
BACKGROUND: Recent genome-wide association (GWA) studies have identified several unsuspected genes associated with type 2 diabetes (T2D) with previously unknown functions. In this investigation, we have examined the role of 9 most significant SNPs reported in GWA studies: [peroxisome proliferator-activated receptor gamma 2 (PPARG2; rs 1801282); insulin-like growth factor two binding protein 2 (IGF2BP2; rs...
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