Article
Association of the PPARGC1A gene polymorphism with diabetic nephropathy in an Asian Indian population (CURES-41).
Metabolic syndrome and related disorders - 1 Apr 2010
Gayathri Sakthi Baby, Radha Venkatesan, Vimaleswaran Karani S, Mohan Viswanathan
Abstract excerpt
BACKGROUND: The aim of this study was to evaluate the association of polymorphisms of the peroxisome proliferator-activated receptor gamma (PPARG) gene and peroxisome proliferators-activated receptor gamma co-activator 1 alpha (PPARGC1A) gene with diabetic nephropathy (DN) in Asian Indians. METHODS: Six common polymorphisms, 3 of the PPARG gene [-1279G/A, Pro12Ala, and His478His (C/T)] and 3 of the PPARGC1A gene...
Topics
- Adult
- Aged
- Amino Acid Substitution
- Asian People
- Diabetic Nephropathies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genetics, Population
- Genome-Wide Association Study