Article
Association studies on 11 published colorectal cancer risk loci.
British journal of cancer - 10 Aug 2010
von Holst S, Picelli S, Edler D, Lenander C, Dalén J, Hjern F, Lundqvist N, Lindforss U, Påhlman L, Smedh K, Törnqvist A, Holm J, Janson M, Andersson M, Ekelund S, Olsson L, Ghazi S, Papadogiannakis N, Tenesa A, Farrington S M, Campbell H, Dunlop M G, Lindblom A
Abstract excerpt
BACKGROUND: Recently, several genome-wide association studies (GWAS) have independently found numerous loci at which common single-nucleotide polymorphisms (SNPs) modestly influence the risk of developing colorectal cancer. The aim of this study was to test 11 loci, reported to be associated with an increased or decreased risk of colorectal cancer: 8q23.3 (rs16892766), 8q24.21 (rs6983267), 9p24 (rs719725), 10p14...
Read the complete abstract on PubMed