Article
The association between the IFIH1 locus and type 1 diabetes.
Diabetologia - 1 Mar 2008
Qu H-Q, Marchand L, Grabs R, Polychronakos C
Abstract excerpt
AIMS/HYPOTHESIS: We set out to validate a recently reported type 1 diabetes association from the IFIH1 gene variation in an independent cohort from a population of mixed European descent. METHODS: We genotyped five single-nucleotide polymorphisms in the IFIH1 locus, i.e. rs2111485, rs1990760, rs3747517, rs17783344 and rs984971589, in 589 type 1 diabetes nuclear family trios (1,767 individuals). RESULTS: This...