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Article

Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae.

Genetics - 1 Jan 2010

Northam Matthew R, Robinson Heather A, Kochenova Olga V, Shcherbakova Polina V

Abstract excerpt

Translesion synthesis DNA polymerases contribute to DNA damage tolerance by mediating replication of damaged templates. Due to the low fidelity of these enzymes, lesion bypass is often mutagenic. We have previously shown that, in Saccharomyces cerevisiae, the contribution of the error-prone DNA polymerase zeta (Polzeta) to replication and mutagenesis is greatly enhanced if the normal replisome is defective due to...

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Identifiers

PMID: 19841096
DOI: 10.1534/genetics.109.107482
PMCID: PMC2815923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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