Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiae.

Biochemistry. Biokhimiia - 1 Jan 2011

Kochenova O V, Soshkina J V, Stepchenkova E I, Inge-Vechtomov S G, Shcherbakova P V

Abstract excerpt

We employed a genetic assay based on illegitimate hybridization of heterothallic Saccharomyces cerevisiae strains (the α-test) to analyze the consequences for genome stability of inactivating translesion synthesis (TLS) DNA polymerases. The α-test is the only assay that measures the frequency of different types of mutational changes (point mutations, recombination, chromosome or chromosome arm loss) and temporary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Fungal
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genomic Instability

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Ultraviolet Rays

Source

Open in PubMed Open full text

Identifiers

PMID: 21568839
DOI: 10.1134/s000629791101007x
PMCID: PMC3174683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in yeast Saccharomyces cerevisiae.PMID 21568839Read ↗

Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutations arising during repair of chromosome breaks.Semantic proximity Read ↗

The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant.Semantic proximity Read ↗

Unlocking the steric gate of DNA polymerase η leads to increased genomic instability in Saccharomyces cerevisiae.Semantic proximity Read ↗

DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone copying of long stretches of adjacent DNA.Semantic proximity Read ↗

DNA damage-induced mutation: tolerance via translesion synthesis.Semantic proximity Read ↗

Stalled replication forks generate a distinct mutational signature in yeast.Semantic proximity Read ↗

The roles of NHEJ and TLS pathways in genomic alterations and phenotypic evolution in the yeast Yarrowia lipolytica.Semantic proximity Read ↗

Mutagenic and recombinagenic responses to defective DNA polymerase delta are facilitated by the Rev1 protein in pol3-t mutants of Saccharomyces cerevisiae.Semantic proximity Read ↗

Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae.Semantic proximity Read ↗

Global genomic instability caused by reduced expression of DNA polymerase ε in yeast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.