Article
Schizophrenia in translation: disrupted in schizophrenia (DISC1): integrating clinical and basic findings.
Schizophrenia bulletin - 1 Jan 2007
Roberts Rosalinda C
Abstract excerpt
The disrupted in schizophrenia 1 (DISC1) gene has been linked to schizophrenia and other serious mental illnesses in multiple pedigrees. This article will review the neurobiology of DISC1 in normal developing and adult brain and the putative role of the mutant form in major mental illness, particularly schizophrenia. The initial genetic finding of an association between DISC1 and schizophrenia in a Scottish...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
