Article

Proteomic Studies Reveal Disrupted in Schizophrenia 1 as a Key Regulator Unifying Neurodevelopment and Synaptic Function

2018-11-19

Abstract excerpt

A balanced chromosomal translocation disrupting DISC1 (Disrupted in Schizophrenia 1) gene has been linked to psychiatric diseases, such as major depression, bipolar disorder and schizophrenia. Since the discovery of this translocation, many studies have focused on understating the role of the truncated isoform of DISC1, hypothesizing that the gain of function of this protein could be behind the neurobiology of men...

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Literature Corpus work: 548917fd-278a-5b23-aeb5-9ebf22113fca
DOI: 10.20944/preprints201811.0467.v1

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