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Article

United detection GNAS and TSHR mutations in subclinical toxic multinodular goiter.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Feb 2010

Liu Chunbo, Yang Jingyuan, Wang Fengjun, Wu Changjun, Zhou Min

Abstract excerpt

The aim of the study was to investigate whether the mutations of the GNAS gene and thyroid-stimulating hormone receptor (TSHR) gene were a potential molecular biological mechanism for subclinical toxic multinodular goiter (sTMG) and to evaluate the association of these mutations with the clinicopathological features of these disorders.Forty-four patients with sTMG and 20 controls(multinodular goiter) from...

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Source

Identifiers

PMID: 19826830
DOI: 10.1007/s00405-009-1051-3

Genes

TSHR
GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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