Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular pathogenesis of euthyroid and toxic multinodular goiter.

Endocrine reviews - 1 Jun 2005

Krohn Knut, Führer Dagmar, Bayer Yvonne, Eszlinger Markus, Brauer Volker, Neumann Susanne, Paschke Ralf

Abstract excerpt

The purpose of this review is to summarize current knowledge of the etiology of euthyroid and toxic multinodular goiter (MNG) with respect to the epidemiology, clinical characteristics, and molecular pathology. In reconstructing the line of events from early thyroid hyperplasia to MNG we will argue the predominant neoplastic character of nodular structures, the nature of known somatic mutations, and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Chromosome Aberrations
Share to Goiter, Nodular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Iodides

Share to Protein Array Analysis

Share to Receptors, Thyrotropin

Share to Thyroid Gland

Source

Identifiers

PMID: 15615818
DOI: 10.1210/er.2004-0005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular pathogenesis of euthyroid and toxic multinodular goiter.PMID 15615818Read ↗

Molecular pathogenesis of nodular goiter.Semantic proximity Read ↗

Mechanisms of disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors.Semantic proximity Read ↗

Molecular aspects of the pathogenesis of nodular goiters, thyroid nodules and adenomas.Semantic proximity Read ↗

Identification of constitutively activating somatic thyrotropin receptor mutations in a subset of toxic multinodular goiters.Semantic proximity Read ↗

Mutations of GNAS and TSHR genes in subclinical toxic multinodular goiter.Semantic proximity Read ↗

[Molecular aetiology of nodular goitre -- consequences for therapy?].Semantic proximity Read ↗

Toxic nodular goiter. Toxic adenoma and toxic multinodular goiter.Semantic proximity Read ↗

United detection GNAS and TSHR mutations in subclinical toxic multinodular goiter.Semantic proximity Read ↗

Evaluation of Downstream Regulatory Element Antagonistic Modulator Gene in Human Multinodular Goiter.Semantic proximity Read ↗

A Novel Germline Mutation of KEAP1 (R483H) Associated with a Non-Toxic Multinodular GoiterSemantic proximity Read ↗

Lack of reported mutations in a Japanese case of toxic multinodular goiter.Semantic proximity Read ↗

Genetic landscape of nodular goiter, thyroid nodules with intermediate features between nodular goiter and follicular adenomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.