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Article

Gain of function TSH receptor mutations and iodine deficiency: implications in iodine prophylaxis.

Journal of endocrinological investigation - 1 Jan 2003

Tonacchera M, Vitti P, De Servi M, Agretti P, De Marco G, Chiovato L, Pinchera A

Abstract excerpt

Iodine deficiency is widely known to be the main cause of nodular goiter (NG). In iodine deficient areas subclinical and overt hyperthyroidism is the major cause of morbidity and it is mainly due to toxic NG rather than Graves' disease. Toxic NG, including toxic multinodular goiter and toxic thyroid adenoma is usually encountered in subjects with long-standing NG, in whom thyrotoxicosis is usually preceded by a...

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Source

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PMID: 12762632

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gain of function TSH receptor mutations and iodine deficiency: implications in iodine prophylaxis.PMID 12762632Read ↗

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