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Article

Is the TSHR D727E polymorphism a genetic predisposition for multinodular goiter in the Turkish population?

Genetics and molecular research : GMR - 5 Aug 2016

Gözü H I, Özçelik S, Aloğlu M, Şahin A, Temiz S, Dayan A, Cengiz H, Tütüncü Y, Bircan R

Abstract excerpt

The D727E germline polymorphism in the thyroid-stimulating hormone receptor gene (TSHR) may cause genetic susceptibility to the development of goiter. Therefore, in this study we investigated allele frequencies and genotype distributions of the TSHR D727E polymorphism, their association with clinical parameters, and the development of goiter in the Turkish population. We investigated the TSHR D727E polymorphism...

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Source

Identifiers

PMID: 27525921
DOI: 10.4238/gmr.15038504

Genes

TSHR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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