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G-quadruplexes may determine the landscape of recombination in HSV-1

16 May 2019

Abstract excerpt

Several lines of evidence suggest that recombination plays a central role in replication and evolution of herpes simplex virus-1 (HSV-1). G-quadruplex (G4)-motifs have been linked to recombination events in human and microbial genomes, but their role in recombination has not been studied in DNA viruses. The availability of near full-length sequences from 40 HSV-1 recombinant strains with exact position of the...

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PMID: 31096907
DOI: 10.1186/s12864-019-5731-0

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