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Article

Inhaled Anesthetic Potency in Aged Alzheimer Mice

15 Jan 2010

Abstract excerpt

BACKGROUND: The number of elderly patients with frank or incipient Alzheimer's disease (AD) requiring surgery is growing as the population ages. General anesthesia may exacerbate symptoms of and the pathology underlying AD, so minimizing anesthetic exposure may be important. This requires knowledge of whether the continuing AD pathogenesis alters anesthetic potency. METHODS: We determined the induction potency...

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PMID: 19820240
DOI: 10.1213/ane.0b013e3181b5a292

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