Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.

Chemical senses - 1 Jun 2016

Roddick Kyle M, Roberts Amelia D, Schellinck Heather M, Brown Richard E

Abstract excerpt

Deficits in odor identification and detection are early symptoms of Alzheimer's disease (AD). Two transgenic mouse models of AD, the 5XFAD and the 3×Tg-AD mice and their wildtype controls, were assessed for olfactory detection with decreasing concentrations of ethyl acetate in a go no-go operant olfactometer task at 6 months of age. For both the 5XFAD and their B6SJLF1 wildtype littermates, females made fewer...

Topics

Join the communities discussing this publication.

Acetates
Alzheimer Disease
Behavior, Animal
Discriminant Analysis
Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Source

Identifiers

PMID: 26969629
DOI: 10.1093/chemse/bjw018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer's Disease at 6 Months of Age.PMID 26969629Read ↗

Alterations in odor hedonics in the 5XFAD Alzheimer’s disease mouse model and the influence of sexSemantic proximity Read ↗

Dissociable cognitive impairments in two strains of transgenic Alzheimer’s disease mice revealed by a battery of object-based testsSemantic proximity Read ↗

Age and gender differences for the behavioral phenotypes of 3xTg alzheimer's disease mice.Semantic proximity Read ↗

Sex Differences between Neuronal Loss and the Early Onset of Amyloid Deposits and Behavioral Consequences in 5xFAD Transgenic Mouse as a Model for Alzheimer’s DiseaseSemantic proximity Read ↗

Visuo‐spatial learning and memory impairments in the 5xFAD mouse model of Alzheimer's disease: Effects of age, sex, albinism, and motor impairmentsSemantic proximity Read ↗

Olfactory Dysfunction and Alzheimer's Disease: A Review.Semantic proximity Read ↗

Evidence for early cognitive impairment related to frontal cortex in the 5XFAD mouse model of Alzheimer's disease.Semantic proximity Read ↗

Sex Differences in Behavior and Molecular Pathology in the 5XFAD Model.Semantic proximity Read ↗

Sex differences in behaviour and molecular pathology in the 5XFAD modelSemantic proximity Read ↗

Age-dependent phenotypic characteristics of a triple transgenic mouse model of Alzheimer disease.Semantic proximity Read ↗

Odor Identification Across Time in Mutation Carriers and Non-Carriers in Autosomal-Dominant Alzheimer's Disease.Semantic proximity Read ↗

Behavioral deficits and exacerbated hemodynamics during lifespan of a mouse model of late onset Alzheimer’s disease expressing humanized APOEε4 and Trem2*R47HSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.