Article
Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jan 2011
Fatini C, Sticchi E, Bolli P, Marcucci R, Giusti B, Paniccia R, Gori A M, Gensini G F, Abbate R
Abstract excerpt
BACKGROUND AND AIM: Platelet nitric oxide (NO) synthesis is compromised in patients with acute coronary syndrome (ACS), and platelet NO availability may be critically relevant in determining the extent of thrombosis in ACS patients. It has been demonstrated that an impaired responsiveness to the antiaggregatory effects of NO may affect platelet dysfunction in diabetic patients with ACS. Since NO availability may...
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