Article
Genetic determinants of platelet reactivity during acetylsalicylic acid therapy in diabetic patients: evaluation of 27 polymorphisms within candidate genes.
Journal of thrombosis and haemostasis : JTH - 1 Nov 2011
Postula M, Kaplon-Cieslicka A, Rosiak M, Kondracka A, Serafin A, Filipiak K J, Czlonkowski A, Opolski G, Janicki P K
Abstract excerpt
AIMS: Decreased platelet responsiveness to acetylsalicylic acid (ASA) reported previously in diabetic patients could be attributed to patient-based, clinical, genetic and cellular factors. The objective of the present study was to investigate the effect of the genomic polymorphism on the platelet reactivity in diabetic patients treated with ASA. METHODS AND RESULTS: The study cohort consisted of 295 Caucasians...
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