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Article

Genetic determinants of on-aspirin platelet reactivity: focus on the influence of PEAR1.

PloS one - 1 Jan 2014

Würtz Morten, Nissen Peter H, Grove Erik Lerkevang, Kristensen Steen Dalby, Hvas Anne-Mette

Abstract excerpt

BACKGROUND: Platelet aggregation during aspirin treatment displays considerable inter-individual variability. A genetic etiology likely exists, but it remains unclear to what extent genetic polymorphisms determine platelet aggregation in aspirin-treated individuals. AIM: To identify platelet-related single nucleotide polymorphisms (SNPs) influencing platelet aggregation during aspirin treatment. Furthermore, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 25360888
DOI: 10.1371/journal.pone.0111816
PMCID: PMC4216141

Genes

PEAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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