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Article

Effect of nitric oxide reduction on arterial thrombosis

2 Jan 2019

Abstract excerpt

OBJECTIVES: Nitric oxide (NO) represents the most powerful endogenous molecule with vasodilator action mainly produced by endothelial nitric oxide synthase (eNOS) enzyme. Polymorphisms and epigenetic-sensitive mechanisms can modulate the expression of eNOS gene, leading to the endothelial dysfunction. This review updates on the mechanistic role of NO in the regulation of platelet activation, as well as the impact...

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Identifiers

PMID: 30741027
DOI: 10.1080/14017431.2019.1581943

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