Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

eNOS gene influences platelet phenotype in acute coronary syndrome patients on dual antiplatelet treatment.

Platelets - 1 Dec 2009

Fatini Cinzia, Sticchi Elena, Bolli Paola, Marcucci Rossella, Giusti Betti, Paniccia Rita, Gori Anna Maria, Gensini Gian Franco, Abbate Rosanna

Abstract excerpt

Nitric Oxide (NO) plays a relevant role in regulating platelet recruitment and eNOS is the major isoform known to be expressed in platelets. Polymorphisms in the eNOS gene with a reduced NO availability might affect platelet phenotype. The aim of our study was to evaluate the role of eNOS-786T > C, 894G > T and 4a/4b polymorphisms in modulating platelet phenotype in 1442 acute coronary syndrome (ACS) patients on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Coronary Syndrome
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged, 80 and over

Share to Blood Platelets

Share to Nitric Oxide Synthase Type III

Share to Platelet Aggregation Inhibitors

Share to Polymorphism, Genetic

Share to Regression Analysis

Source

Identifiers

PMID: 19891529
DOI: 10.3109/09537100903337401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

eNOS gene influences platelet phenotype in acute coronary syndrome patients on dual antiplatelet treatment.PMID 19891529Read ↗

Platelet aggregability is modulated by eNOS locus in non-type 2 diabetic patients with acute coronary syndrome.Semantic proximity Read ↗

Genetically Determined Platelet Reactivity and Related Clinical Implications.Semantic proximity Read ↗

Adrenergic receptor polymorphisms and platelet reactivity after treatment with dual antiplatelet therapy with aspirin and clopidogrel in acute coronary syndrome.Semantic proximity Read ↗

Lack of association between the 807 C/T polymorphism of glycoprotein Ia gene and post-treatment platelet reactivity after aspirin and clopidogrel in patients with acute coronary syndrome.Semantic proximity Read ↗

Genetic determinants of on-aspirin platelet reactivity: focus on the influence of PEAR1.Semantic proximity Read ↗

Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations.Semantic proximity Read ↗

Role of glycoprotein Ia gene polymorphisms in determining platelet function in myocardial infarction patients undergoing percutaneous coronary intervention on dual antiplatelet treatment.Semantic proximity Read ↗

Pharmacogenetics of the antiplatelet effect of aspirin.Semantic proximity Read ↗

Effects of endothelial nitric oxide synthase gene polymorphisms on platelet function, nitric oxide release, and interactions with estradiol.Semantic proximity Read ↗

Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin.Semantic proximity Read ↗

Prospective Evaluation of Genetic Variation in Platelet Endothelial Aggregation Receptor 1 Reveals Aspirin-Dependent Effects on Platelet Aggregation Pathways.Semantic proximity Read ↗

The role of clinical parameters and of CYP2C19 G681 and CYP4F2 G1347A polymorphisms on platelet reactivity during dual antiplatelet therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.