Article
Genetically Determined Platelet Reactivity and Related Clinical Implications.
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension - 1 Sept 2015
Strisciuglio Teresa, Di Gioia Giuseppe, De Biase Chiara, Esposito Massimiliano, Franco Danilo, Trimarco Bruno, Barbato Emanuele
Abstract excerpt
Many drugs are nowadays available to inhibit platelet activation and aggregation, especially in patients with acute coronary syndromes and undergoing percutaneous coronary intervention with stent implantation. Primary targets are represented by enzymes or receptors involved in platelet activation. Genetic mutations in these targets contribute to the inter-individual variability in platelet responses therefore...
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