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Article

Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II.

The EMBO journal - 15 Jun 2005

Bucheli Miriam E, Buratowski Stephen

Abstract excerpt

Proper 3' end formation is critical for the production of functional mRNAs. Termination by RNA polymerase II is linked to mRNA cleavage and polyadenylation, but it is less clear whether earlier stages of mRNA production also contribute to transcription termination. We performed a genetic screen to identify mutations that decreased transcriptional readthrough of a defective GAL10 poly(A) terminator. A partial...

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Identifiers

PMID: 15902270
DOI: 10.1038/sj.emboj.7600687
PMCID: PMC1150882

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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