Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Futile cycle of transcription initiation and termination modulates the response to nucleotide shortage in S. cerevisiae.

Molecular cell - 5 Sept 2008

Thiebaut Marilyne, Colin Jessie, Neil Helen, Jacquier Alain, Séraphin Bertrand, Lacroute François, Libri Domenico

Abstract excerpt

Hidden transcription in eukaryotes carries a large potential of regulatory functions that are only recently beginning to emerge. Cryptic unstable transcripts (CUTs) are generated by RNA polymerase II (Pol II) and rapidly degraded after transcription in wild-type yeast cells. Whether CUTs or the act of transcription without RNA production have a function is presently unclear. We describe here a nonconventional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Flanking Region
Share to Aspartate Carbamoyltransferase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Nucleotides

Share to Regulatory Sequences, Nucleic Acid

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Terminator Regions, Genetic

Source

Identifiers

PMID: 18775327
DOI: 10.1016/j.molcel.2008.08.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Futile cycle of transcription initiation and termination modulates the response to nucleotide shortage in S. cerevisiae.PMID 18775327Read ↗

Phosphorylation of the RNA polymerase II C-terminal domain dictates transcription termination choice.Semantic proximity Read ↗

Transcription termination and nuclear degradation of cryptic unstable transcripts: a role for the nrd1-nab3 pathway in genome surveillance.Semantic proximity Read ↗

Fail-safe transcriptional termination for protein-coding genes in S. cerevisiae.Semantic proximity Read ↗

Crosstalk between mRNA 3' end processing and transcription initiation.Semantic proximity Read ↗

Properties of an intergenic terminator and start site switch that regulate IMD2 transcription in yeast.Semantic proximity Read ↗

Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability.Semantic proximity Read ↗

A single-stranded promoter for RNA polymerase III.Semantic proximity Read ↗

cis- and trans-Acting determinants of transcription termination by yeast RNA polymerase II.Semantic proximity Read ↗

Transcription directionality is licensed by Integrator at active human promotersSemantic proximity Read ↗

Chromatin-sensitive cryptic promoters encode alternative protein isoforms in yeastSemantic proximity Read ↗

mRNA 3' tagging is induced by nonsense-mediated decay and promotes ribosome dissociation.Semantic proximity Read ↗

An alternate mechanism of abortive release marked by the formation of very long abortive transcripts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.