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CD133 Expression Defines a Tumor Initiating Cell Population in Primary Human Ovarian Cancer

8 Oct 2009

Abstract excerpt

Evidence is accumulating that solid tumors contain a rare phenotypically distinct population of cells, termed cancer stem cells (CSC), which give rise to and maintain the bulk of the tumor. These CSC are thought to be resistant to current chemotherapeutic strategies due to their intrinsic stem-like properties and thus may provide the principal driving force behind recurrent tumor growth. Given the high frequency...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19816957
DOI: 10.1002/stem.236

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