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Article

Imaging and analysis of 3D tumor spheroids enriched for a cancer stem cell phenotype.

Journal of biomolecular screening - 1 Aug 2010

Robertson Fredika M, Ogasawara Marcia A, Ye Zaiming, Chu Khoi, Pickei Ross, Debeb Bisrat G, Woodward Wendy A, Hittelman Walter N, Cristofanilli Massimo, Barsky Sanford H

Abstract excerpt

Tumors that display a highly metastatic phenotype contain subpopulations of cells that display characteristics similar to embryonic stem cells. These cells exhibit the ability to undergo self-renewal; slowly replicate to retain a nucleoside analog label, leading to their definition as "label-retaining cells"; express specific surface markers such as CD44(+)/CD24(-/low) and CD133; and can give rise to cells of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20639504
DOI: 10.1177/1087057110376541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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