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Article

Ovarian cancer cells with the CD117 phenotype are highly tumorigenic and are related to chemotherapy outcome.

Experimental and molecular pathology - 1 Oct 2011

Luo Lijing, Zeng Jianfang, Liang Bing, Zhao Zhe, Sun Lulu, Cao Dongyan, Yang Jiaxin, Shen Keng

Abstract excerpt

Cancer stem cells (CSCs) play an important role in the recurrence and drug resistance of cancer. Isolation and characterization of CSCs from ovarian cancer samples may help to provide novel diagnostic and therapeutic targets in the management of recurrent disease and drug resistance in ovarian cancer. Here, we developed a xenograft model in which cells from 14 samples of human ovarian serous adenocarcinoma tissue...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21787767
DOI: 10.1016/j.yexmp.2011.06.005

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