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Article

Epithelial ovarian cancer stem cells: underlying complexity of a simple paradigm

9 Oct 2014

Abstract excerpt

The lack of significant progress in the treatment of epithelial ovarian cancer (EOC) underscores the need to gain a better understanding of the processes that lead to chemoresistance and recurrence. The cancer stem cell (CSC) hypothesis offers an attractive explanation of how a subpopulation of cells within a patient's tumour might remain refractory to treatment and subsequently form the basis of recurrent...

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PMID: 25301968
DOI: 10.1530/rep-14-0234

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