Article
Identification of four novel potentially Parkinson's disease associated LRRK2 variations among Iranian patients.
Neuroscience letters - 25 Dec 2009
Shojaee Seyedmehdi, Fazlali Zeinab, Ghazavi Farzaneh, Banihosseini Setareh Sadat, Kazemi Mohammad Hossein, Parsa Khosro, Sadeghi Homa, Sina Farzad, Shahidi Gholam-Ali, Ronaghi Mostafa, Elahi Elahe
Abstract excerpt
The results of mutation screening of 24 exons of LRRK2 in 60 Iranian Parkinson's Disease patients are presented. The Iranian cohort represents a novel population and was notably young (average age at onset of disease: 36.0 years). Fifty sequence variations were found, seventeen of which are novel. Variations considered possibly associated with disease were screened in available family members, 145 additional...
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