Article
A clinic-based screening of mutations in exons 31, 34, 35, 41, and 48 of LRRK2 in Iranian Parkinson's disease patients.
Movement disorders : official journal of the Movement Disorder Society - 15 May 2009
Shojaee Seyedmehdi, Sina Farzad, Farboodi Niloofar, Fazlali Zeinab, Ghazavi Farzaneh, Ghorashi Seyed Ali, Parsa Khosro, Sadeghi Homa, Shahidi Gholam-Ali, Ronaghi Mostafa, Elahi Elahe
Abstract excerpt
We present results of mutation screening of exons 31, 34, 35, 41, and 48 of LRRK2 in 205 Iranian Parkinson's disease patients. Sixteen percent of the cases were familial. Although age was not a factor in patient recruitment, the Iranian cohort was relatively young (average age at onset of disease: 48.9 years). A notably high male to female ratio (2.96:1) and earlier age at onset (by 2.9 years) in men were...
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