Article

Physoxia influences global and gene-specific methylation in pluripotent stem cells

2022-03-22

Abstract excerpt

Pluripotent stem cells (PSC) possess unlimited proliferation, self-renewal, and a differentiation capacity spanning all germ layers. Appropriate culture conditions are important for the maintenance of self-renewal, pluripotency, proliferation, differentiation, and epigenetic states. Oxygen concentrations vary across different human tissues depending on precise cell location and proximity to vascularisation. The bu...

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Literature Corpus work: 8c1cd5d1-d0f2-551a-aa77-232d3b288fee
DOI: 10.1101/2022.03.21.484908

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