Hypoxia Signaling and Placental Adaptations.

doi:10.1007/978-1-4939-7665-2_15

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Article

Hypoxia Signaling and Placental Adaptations.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Chakraborty Damayanti, Scott Regan L, Soares Michael J

Abstract excerpt

Oxygen is an essential nutrient for cells. Oxygen is delivered to tissues via red blood cells through the vasculature. Molecular mechanisms mediating cellular responses to low oxygen tension have been identified. Hypoxia-inducible factors (HIFs) are activated by low oxygen and promote transcriptional regulation of downstream effector genes, which lead to cellular adaptations. Controlled hypoxia exposure is...

Topics

Adaptation, Physiological
Animals
Cell Hypoxia
Female
Gene Expression Profiling
Gene Regulatory Networks
Oxygen
Phenotype
Placenta
Pregnancy
Rats
Signal Transduction
Trophoblasts

Source

Open in PubMed

Identifiers

PMID: 29330799
DOI: 10.1007/978-1-4939-7665-2_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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