Article
Folate nutritional genetics and risk for hypertension in an elderly population sample.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2009
Ng Xiaowei, Boyd Lyndell, Dufficy Lisa, Naumovski Nenad, Blades Barbara, Travers Cheryl, Lewis Peter, Sturm Jonathon, Yates Zoë, Townley-Jones Maureen, Roach Paul, Veysey Martin, Lucock Mark
Abstract excerpt
BACKGROUND/AIMS: 118 elderly participants (65-90 years) were assessed for any relationship between folate, related genes and hypertension. METHODS: Six B-vitamin-related SNPs were genotyped in 80 normotensive and 38 hypertensive subjects. RESULTS: Of six polymorphisms (677C>T-MTHFR, 1298A>C-MTHFR, 80G>A-RFC, 2756A>G-MS, 66A>G- MSR, 19bpDHFR and 1561C>T-GCPII), only 677C>T-MTHFR was a significant risk for...
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