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Article

B-vitamins, methylenetetrahydrofolate reductase (MTHFR) and hypertension.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition - 1 Jul 2011

Ward Mary, Wilson Carol P, Strain J J, Horigan Geraldine, Scott John M, McNulty Helene

Abstract excerpt

Hypertension is a leading risk factor for cardiovascular disease (CVD) and stroke. A common polymorphism in the gene encoding the enzyme methylenetetrahydrofolate reductase (MTHFR), previously identified as the main genetic determinant of elevated homocysteine concentration and also recognized as a risk factor for CVD, appears to be independently associated with hypertension. The B-vitamin riboflavin is required...

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Identifiers

PMID: 22237773
DOI: 10.1024/0300-9831/a000069

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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