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Article

Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults.

Blood - 1 Apr 2003

Kluijtmans Leo A J, Young Ian S, Boreham Colin A, Murray Liam, McMaster Dorothy, McNulty Helene, Strain J J, McPartlin Joseph, Scott John M, Whitehead Alexander S

Abstract excerpt

A modestly elevated total plasma homocysteine concentration (tHcy) is generally accepted as an independent and graded risk factor for various pathologies, including vascular diseases, neural tube defects, Alzheimer disease, and pregnancy complications. We analyzed 5 common functional polymorphisms in enzymes involved in homocysteine metabolism (ie, methylenetetrahydrofolate reductase [MTHFR] 677C>T and 1298A>C,...

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Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
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Source

Identifiers

PMID: 12642343
DOI: 10.1182/blood.V101.7.2483

Genes

MTHFR
CBS
MTR
MTRR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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