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Article

Effects of MTHFR A1298C polymorphism on peripheral blood folate concentration in healthy populations: a meta-analysis of observational studies.

Asia Pacific journal of clinical nutrition - 1 Jan 2000

Xin Yu, Wu Lihua, Lu Xiaolin, Shangguan Shaofang, Wang Zhen, Chang Shaoyan, Yin Jiyong, Piao Wei, Zhang Ting, Wang Li

Abstract excerpt

BACKGROUND AND OBJECTIVES: Methylenetetrahydrofolate reductase (MTHFR) irreversibly converts 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, which is the main form of folate used in the body. Previous studies suggest that MTHFR polymorphism influences folate metabolism, but conflicting results are reported. We performed a meta-analysis to accurately characterize the association between MTHFR A1298C...

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Share to Folic Acid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29737822
DOI: 10.6133/apjcn.122017.02

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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