Article
Interactions of Methylenetetrahydrofolate Reductase Gene Polymorphisms, Folate, and Homocysteine on Blood Pressure in a Chinese Hypertensive Population.
Clinical laboratory - 1 Apr 2017
Li Wen-Xing, Liao Peng, Hu Chao-Yue, Cheng Fei, Zhang Tao, Sun Yuan-Yuan, Tang Ling, Wang Man-Man, Liu Kui-Sheng, Liu Dahai, Liu Fang
Abstract excerpt
BACKGROUND: High blood pressure is related to cardiovascular diseases. We aimed to explore the interactions of methylenetetrahydrofolate reductase (MTHTR) gene C677T and A1298C mutations and folate/homocysteine (Hcy) status on blood pressure in a Chinese hypertensive population. METHODS: The clinical data in the present study derived from a previous trial (NCT00520247). Genotypes in Hcy pathway enzymes were...
Topics
- Blood Pressure
- Folic Acid
- Genotype
- Homocysteine
- Humans
- Hypertension
- Methylenetetrahydrofolate Reductase (NADPH2)
- Polymorphism, Single Nucleotide