Article
Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2008
Steck Susan E, Keku Temitope, Butler Lesley M, Galanko Joseph, Massa Beri, Millikan Robert C, Sandler Robert S
Abstract excerpt
BACKGROUND/AIMS: We examined associations among folate and alcohol intake, single nucleotide polymorphisms (SNPs) in genes involved in one-carbon metabolism, and colon cancer risk. METHODS: Colon cancer cases (294 African-Americans and 349 whites) were frequency matched to population controls (437 African-Americans and 611 whites) by age, race and sex from 33 North Carolina counties from 1996 to 2000. Folate and...
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