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Article

B-vitamin intake, metabolic genes, and colorectal cancer risk (United States).

Cancer causes & control : CCC - 1 Apr 2002

Le Marchand Loïc, Donlon Timothy, Hankin Jean H, Kolonel Laurence N, Wilkens Lynne R, Seifried Ann

Abstract excerpt

OBJECTIVE: This population-based case-control study was designed to investigate the interrelationships between polymorphisms in the methylenetetrahydrofolate (MTHFR C677T and A1298C) gene and other genes (MTR A2756G; MTRR A66G and CBS 844ins68), intake of B-vitamins and colorectal cancer risk (CRC). METHODS: We interviewed 727 CRC cases of Japanese, Caucasian, or Native Hawaiian origin and 727 controls matched on...

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Identifiers

PMID: 12020105
DOI: 10.1023/a:1015057614870

Genes

MTHFR
CBS
MTR
MTRR

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