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Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1

24 Sept 2009

Abstract excerpt

Formation of the germ cell lineage involves multiple processes, including repression of somatic differentiation and reacquisition of pluripotency as well as a unique epigenetic constitution. The transcriptional regulator Prdm1 has been identified as a main coordinator of this process, controlling epigenetic modification and gene expression. Here we report on the expression pattern of the transcription factor...

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PMID: 19776388
DOI: 10.1095/biolreprod.109.078717

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