Article
Transcription factor AP-2gamma is essential in the extra-embryonic lineages for early postimplantation development.
Development (Cambridge, England) - 1 Jun 2002
Auman Heidi J, Nottoli Timothy, Lakiza Olga, Winger Quinton, Donaldson Stephanie, Williams Trevor
Abstract excerpt
The members of the AP-2 family of transcription factors play important roles during mammalian development and morphogenesis. AP-2gamma (Tcfap2c - Mouse Genome Informatics) is a retinoic acid-responsive gene implicated in placental development and the progression of human breast cancer. We show that AP-2gamma is present in all cells of preimplantation embryos and becomes restricted to the extra-embryonic lineages...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
