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Article

Ethnic variation in genotype frequencies of delta-aminolevulinic acid dehydratase (ALAD).

Toxicology letters - 15 Dec 2009

Fujihara Junko, Agusa Tetsuro, Yasuda Toshihiro, Soejima Mikiko, Kato Hideaki, Panduro Arturo, Koda Yoshiro, Kimura-Kataoka Kaori, Takeshita Haruo

Abstract excerpt

Delta-aminolevulinic acid dehydratase (ALAD) is a cytosolic enzyme in the heme biosynthetic pathway. The ALAD is controlled by two codominant alleles (ALAD1 and ALAD2), which result in a Asn-Lys substitution at amino acid position 59 of the mature enzyme based on a single nucleotide polymorphism (SNP) (G177C) leading three phenotypes (ALAD1-1, ALAD1-2, and ALAD2-2). Previous studies have shown that this...

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Identifiers

PMID: 19766174
DOI: 10.1016/j.toxlet.2009.09.005

Genes

ALAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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