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Article

Ethnicity affects the distribution of delta-aminolevulinic acid dehydratase (ALAD) genetic variants.

Clinica chimica acta; international journal of clinical chemistry - 1 May 2006

Montenegro Marcelo F, Barbosa Fernando, Sandrim Valeria C, Gerlach Raquel F, Tanus-Santos Jose E

Abstract excerpt

BACKGROUND: delta-Aminolevulinic acid dehydratase (ALAD) catalyzes the second step of heme synthesis. The ALAD gene shows a polymorphism (G-to-C transversion at position 177) leading to 2 alleles (ALAD1 and ALAD2) and 3 phenotypes (ALAD 1-1, ALAD 1-2 and ALAD 2-2). This polymorphism has been shown to affect lead toxicity and the risk of meningioma. In addition, there is little evidence showing interethnic...

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Source

Identifiers

PMID: 16445899
DOI: 10.1016/j.cca.2005.12.009

Genes

ALAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ethnicity affects the distribution of delta-aminolevulinic acid dehydratase (ALAD) genetic variants.PMID 16445899Read ↗

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