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Delta-aminolevulinic acid dehydratase polymorphism and risk of brain tumors in adults.

Environmental health perspectives - 1 Sept 2005

Rajaraman Preetha, Schwartz Brian S, Rothman Nathaniel, Yeager Meredith, Fine Howard A, Shapiro William R, Selker Robert G, Black Peter M, Inskip Peter D

Abstract excerpt

The enzyme delta-aminolevulinic acid dehydratase (ALAD), which catalyzes the second step of heme synthesis, can be inhibited by several chemicals, including lead, a potential risk factor for brain tumors, particularly meningioma. In this study we examined whether the ALAD G177C polymorphism in the gene coding for ALAD is associated with risk of intracranial tumors of the brain and nervous system. We use data from...

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Identifiers

PMID: 16140629
DOI: 10.1289/ehp.7986
PMCID: PMC1280403

Genes

ALAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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