Article
Genotyping an ALAD polymorphism with real-time PCR in two populations from the Iberian Peninsula.
Biochemical genetics - 1 Aug 2012
Moreira Ana O, Almeida André, Costa Solange, Laffon Blanca, García-Léston Julia, Pásaro Eduardo, Méndez Josefina, Teixeira João Paulo
Abstract excerpt
Lead-induced toxicity varies among individuals partly because of genetic differences in their susceptibility to the metal's effects. One genetic polymorphism associated with lead toxicity is a G-to-C transversion at position 177 in the coding region of delta-aminolevulinic acid dehydratase (ALAD), originating from two codominant alleles (ALAD1 and ALAD2). We examined the distribution of this single nucleotide...
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